基于PCR技术的DNA甲基化检测方法研究进展
李克勇;肖武生;常秀丽;吴庆;
摘要(Abstract):
DNA甲基化是表观遗传修饰最基本的方式,在维持正常细胞功能、胚胎发育和肿瘤发生中起着重要的作用,是当前学术研究的重点和热点。随着研究的深入,为满足不同研究目的需求,DNA甲基化检测方法也得到了较快的发展。本文针对近年来基于PCR技术的DNA甲基化检测方法进行简要的分析总结,为选择适合研究目的的检测方法提供帮助。
关键词(KeyWords): 表观遗传;DNA甲基化;PCR;检测
基金项目(Foundation): 国家自然科学基金(30671728,30630021)
作者(Authors): 李克勇;肖武生;常秀丽;吴庆;
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